Scientists grow dinosaur snout in a chicken

New York: In a first, a team led by an Indian-origin researcher has successfully replicated the molecular processes that led from dinosaur snouts to the first bird beaks by 'growing' the snout that replaced a chicken's beak in the lab. Using the fossil record, the team led by paleontologist and developmental biologist Bhart-Anjan Bhullar from Yale University conducted the first successful reversion of a bird's skull features in the lab.

They replicated ancestral molecular development to transform chicken embryos in a lab into specimens with a snout and palate configuration similar to that of small dinosaurs such as Velociraptor and Archaeopteryx. First, they did a quantitative analysis of the anatomy of related fossils and extant animals to generate a hypothesis about the transition.

Next, they searched for possible shifts in gene expression that correlated with the transition. The team looked at gene expression in the embryos of emus, alligators, lizards and turtles. The researchers discovered that both major living lineages of birds differ from the major lineages of non-bird reptiles and from mammals in having a unique, median gene expression.

This median gene expression had previously only been observed in chickens. The researchers were able to induce the ancestral molecular activity and the ancestral anatomy.Not only did the beak structure revert but the process also caused the palatine bone on the roof of the mouth to go back to its ancestral state.