Scientists create talking neurons

Scientists create talking neurons
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Highlights

Scientists have perfected mini-cultured 3D structures that grow and function much like the outer tissue (cortex) of the brain of the person from whom they were harvested. Strikingly, these \"organoids\" buzz with neuronal network activity where cells talk with each other in circuits much as they do in our brains.

Washington: Scientists have perfected mini-cultured 3D structures that grow and function much like the outer tissue (cortex) of the brain of the person from whom they were harvested. Strikingly, these "organoids" buzz with neuronal network activity where cells talk with each other in circuits much as they do in our brains.


This evolving "disease-in-a-dish" technology is bringing closer the day when patients can ask for personalised medicines, said the study, funded by the US National Institutes of Health (NIH). "The cortex spheroids grow to a state in which they express functional connectivity, allowing for modeling and understanding of mental illnesses," said Thomas R Insel, director of the National Institute of Mental Health.


Like the developing brain, the neurons form layers and talk with each other via neural networks. "While the technology is still maturing, there is great potential for using these assays to more accurately develop, test safety and effectiveness of new treatments before they are used in individuals with a mental illness," said David Panchision, programme director for stem cell research

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