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3D micro heart muscle offers cheaper drug tests
A team of US scientists has invented a new way to create three-dimensional (3D) human heart tissue from stem cells that offers cheaper and faster method to create heart tissue for testing drugs and modelling disease.
New York: A team of US scientists has invented a new way to create three-dimensional (3D) human heart tissue from stem cells that offers cheaper and faster method to create heart tissue for testing drugs and modelling disease.
The tissue also opens the door for a precision medicine approach to treating heart disease. "We have bioengineered micro-scale heart tissues with a method that can easily be reproduced, which will enable scientists in stem cell biology and the drug industry to study heart cells in their proper context," said Nathaniel Huebsch, postdoctoral fellow at San Francisco-based at the Gladstone Institutes.
"In turn, this will enhance our ability to discover treatments for heart disease," Huebsch added.Creating heart cells from induced pluripotent stem cells (iPSCs) that are derived from a patient's skin cells is inadequate for drug testing because they do not properly predict how a drug will affect adult heart cells.
