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UoH team develops novel nano carrier to treat cancer
The University of Hyderabad team of School of Engineering Sciences have designed and developed a novel and biocompatible polymer based nano drug carriers with high potential impact of immune therapy and cancer treatment.
Hyderabad: The University of Hyderabad team of School of Engineering Sciences have designed and developed a novel and biocompatible polymer based nano drug carriers with high potential impact of immune therapy and cancer treatment.
Dr Pradip Paik, associate professor of the School of Engineering Sciences and Technology of the university and his research group developed the polymer based drug carrier.
These nano carriers exhibited attractive properties of drug encapsulation and controlled release of the same for sustained and prolonged release of NO (Nitric Oxide) in macrophages. This work has been collaborated with Dr Hridayesh Prakash (Ramanujan Fellow, School of Life Sciences at UoH). Anil Kumar, Scholar of Paik’s research group and Dr Vinodh Nadella are also the co-contributors for this invention.
This invention presents for the first time the design of hollow poly-N-acryloyl L-phenyl alanine methyl ester (NAPA-HPN’s) bio degradable nano-capsules of average size ranging from 100-150 nm. These capsules are mono dispersed with high stability (with surface charge) and very much promising for sustained delivery of immune-modular drugs for their prolonged action.
The NAPA-HPN nano-capsules could be used for the effective management of various infections or tumour diseases where immune stimulation is paramount.
