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Human heart on a chip to aid drug tests
Highlights
Scientists - including an Indian American bioengineer - have developed a network of pulsating cardiac muscle cells housed in an inch-long silicone device that effectively models human heart tissue. The team has demonstrated the viability of this system as a drug-screening tool by testing it with cardiovascular medications. This organ-on-a-chip represents a major step forward in the development of accurate, faster methods of testing for drug toxicity.
New York: Scientists - including an Indian American bioengineer - have developed a network of pulsating cardiac muscle cells housed in an inch-long silicone device that effectively models human heart tissue. The team has demonstrated the viability of this system as a drug-screening tool by testing it with cardiovascular medications. This organ-on-a-chip represents a major step forward in the development of accurate, faster methods of testing for drug toxicity. The heart cells were derived from human-induced pluripotent stem cells, the adult stem cells that can be coaxed to become many different types of tissue.
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